STAT3 Transcription Factor

A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.

Also Known As:

Signal Transducer and Activator of Transcription 3; APRF Transcription Factor; Acute-Phase Response Factor; IL6-Response Factor; LIF-Response Factor; STAT3 Protein; STAT3a Transcription Factor; STAT3b Transcription Factor; Stat3alpha Transcription Factor; Stat3beta Transcription Factor; Acute Phase Response Factor; IL6 Response Factor; LIF Response Factor; Response Factor, Acute-Phase; Transcription Factor, APRF; Transcription Factor, STAT3; Transcription Factor, STAT3a; Transcription Factor, STAT3b; Transcription Factor, Stat3alpha; Transcription Factor, Stat3beta

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Transcription Factors: 39842
    - STAT Transcription Factors: 46
      - STAT3 Transcription Factor: 2884
  - Carrier Proteins: 13306
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT3 Transcription Factor: 2884
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT3 Transcription Factor: 2884
- Peptides: 84029
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT3 Transcription Factor: 2884

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Disease

Drug/Important Bio-Agent (IBA)